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Key takeaways Cotinine testing, while widely used to detect nicotine exposure, has limitations in distinguishing between active smokers, passive smokers, and users of nicotine replacement therapies due to varying cut-off values and the influence of multiple factors on cotinine levels

[52] The adolescent brain seems to be particularly sensitive to neuroplasticity as a result of nicotine

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Quitting Resources Cigarette Smoking: Health Risks and How to Quit (PDQ)Patient Version