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Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB

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The cohort included two sub-groups ( n = 8 per sub-group) based on length of response to CAR T cells, with short-term responders (STR) having CD19+ leukemia relapse within 142 30 days following initial response and long-term responders (LTR) maintaining remission without subsequent therapy post-CAR T cell infusion