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Janeczko, MPH Cardiology | July 24, 2026 Explore how the Cardiovascular-Kidney-Metabolic framework changes risk assessment and multisystem management strategies

The SUSTAIN-6 trial showed reduced risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease

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These findings suggest that the effects of SGLT2 inhibitors extend beyond hemodynamic improvements, involving direct modulation of intracellular pathways implicated in kidney injury