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Centre for Vascular Research School of Medical Sciences (Pathology) and Bosch Institute Sydney Medical School The University of Sydney Sydney, New South Wales, Australia Copyright 2003-2026 Linus Pauling Institute Figure Alternative Text Figure 1

Researchers studying metabolic dysfunction in adipose tissue have identified NNMT as one of the most consistently upregulated enzymes in obese white fat, making it a high-confidence therapeutic target for metabolic intervention

The integration of AI in R&D, coupled with synthetic biological systems that mimic metabolic processes and the monitoring of digital biomarkers, could also allow weight management to become more effective, accessible and personalised

Lemon, honey, aloe vera, turmeric, cucumber, papaya, orange peel, and potatoes are the most effective natural ingredients that you can apply in different home remedies to help with skin brightening

The heterogeneity between studies was examined by DerSimonian and Laird (DL) Q statistical analysis.17 The I2 statistic was used to estimate the percentage of variability across studies attributable to heterogeneity beyond chance