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Semaglutide reduced ELF score and VCTE-measured liver stiffness, and improved N-terminal type III collagen propeptide (PRO-C3) and the FibroScan-AST (FAST) score, markers associated with fibrotic activity and risk stratification in MASLD [7,13,14]
Mostly regulatory and marketing reasons
It starts with a low tolerability dose, increases through a structured titration schedule, and settles into a maintenance level that varies by patient
The sensation of fullness often begins within the first few weeks of treatment and tends to persist throughout the duration of therapy
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