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It is used in addition to diet and exercise for long-term weight management in: Adults with obesity and adults with overweight and with at least one other weight-related medical issue, like high cholesterol or high blood pressure (injection and pill)

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PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

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[DOI] [PubMed] [Google Scholar] 5.Pinchevsky Y., Butkow N., Raal F.J., Chirwa T., Rothberg A