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70,72 In addition, in murine PDX models of human malignant phyllodes tumors, the CCL5-CCR5 axis that was blocked by the FDA-proved CCR5 inhibitor, maraviroc, suppressed macrophage recruitment to the tumor, significantly retarding tumor growth

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The multiple health hazards that have been associated with smoking addiction have raised the need for safe and effective treatments able to facilitate smoking cessation