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In metabolic disorders such as T2D and obesity, a dysbiotic, low-SCFA microbiome, often characterized by a higher Bacillota-to-Bacteroidota ratio and a depletion of Akkermansia muciniphila, is associated with impaired baseline incretin secretion, contributing to insulin resistance (6972)

Data availability No new, previously unpublished patient data were generated or analyzed in support of this research

MECOVON 1000 INJECTION 1ML can be administered intravenously or intramuscularly

It is a triple-receptor agonist that simultaneously targets GLP-1, GIP and glucagon receptors

While their physical health benefits are well documented, the effects of GLP-1 medications on mental health are less clear but increasingly important