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Other longitudinal research, however, has suggested regular e-cigarette use is associated with an increased likelihood of attempting to quit and with a substantial reduction in cigarette consumption, but not with smoking cessation at a 6-month follow-up [21] or 1-year follow-up [22], and that frequent or daily e-cigarette use is associated with higher odds of quitting smoking [23,24,25], but also with a significantly higher probability of relapse to smoking among men [26]

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