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Some members have noticed major improvements: Others lost weight or improved their diabetes control but didnt see a change in HS: GLP-1s are relatively new, so healthcare professionals are still learning how they affect HS

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Recent structural and mechanistic advancesmost notably the catalytic cysteine trisulfideclarify how membrane context and substrate availability tune catalytic flux, yet debate persists over the physiological sulfur acceptor (glutathione versus sulfite) and how microenvironments route sulfide