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Richie, professor of Public Health Sciences and Pharmacology at Penn State University College of Medicine in Hershey, has studied glutathione for over 30 years

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In some embodiments is an enhanced viscosity formulation, comprising from about 0.1 mM and about 100 mM of an active agent, a pharmaceutically acceptable viscosity enhancer or viscosity modulating agent, and water for injection, the concentration of the viscosity enhancer or viscosity modulating agent in the water being sufficient to provide an enhanced viscosity formulation with a final viscosity from about 100 to about 100,000 cP

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Accordingly, whereas D 4 R fails to mediate the nuclear translocation of G and arrestin3 under desensitization conditions (Additional file 1: Fig