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For instance, Virginia tobacco features a high pH and a concentrated amounts of it in a blend may cause tongue bite

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This hypothesis suggests that neurotransmitter dysfunction such as dopamine, serotonin, glutamine, gamma-aminobutyric acid, and acetylcholine, which is a key pathological factor of schizophrenia, is improved, as smoking stimulates the activities of these neurotransmitters via various mechanisms [32, 33]