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Moreover, these redox reactions form the basis for the post-translational modulation (PTM) of a wide range of proteins that regulate not only metabolism but also ROS signalling and proteinprotein interactions, such as those of the chloroplast CP12-2/phosphoribulokinase (PRK)/glyceraldehyde 3-phosphate dehydrogenase (GAPB) ternary complex

Both classes lower blood glucose, promote weight loss, and reduce cardiovascular risk, but SGLT2 inhibitors have stronger evidence for kidney and heart failure protection and are generally preferred in those conditions