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PMID 19546159

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For instance, most vapor product users also smoke or previously smoked cigarettes.[21] With this in mind, we can imagine the behaviors of vapers to mirror those of smokers

Collectively, these studies demonstrate that smokeless tobacco induces oral microbiome dysbiosis characterized by enrichment of pro-inflammatory taxa (e.g., Fusobacterium and Prevotella ), depletion of symbiotic species (e.g., Lactobacillus and Neisseria ), and activation of carcinogenesis-linked metabolic pathways (nitrogen metabolism and LPS biosynthesis), with dose-dependent effects and product-specific virulence

Skin Substances in tobacco smoke can change the structure of your skin