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In the TME of chronic hypoxia and nutritional deficiency, exosomes secreted by CAF carry significant lactate, acetate, and amino acids to promote tumour metabolism, including PPP, glutamine decomposition, and nucleotide metabolism

doi: 10.1186/s13045-020-00990-3 261 KoikeHHaradaMKusamotoAKunitomiCXuZTanakaTet al

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