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Long-Term Effects of Nicotine & Anxiety Long-term exposure to nicotine has been linked to an increased risk of developing panic disorders and GAD

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Frequent marijuana use causes the same negative effects

Within the broad scope of research topics in the literature, the papers selected for this review focused on e-cigarettes in the context of key topics related to tobacco harm reduction, including aerosol chemistry studies, toxicological assessments of e-cigarette aerosols with in vitro and in vivo in comparison to cigarette smoke, and clinical investigations that examined the short- and long-term benefits of switching to e-cigarettes for adult smokers (Table 1)