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Involvement of substrate analogs in the pathway could also lead to nicotine analogs as with 2- and 6-methylnicotinic acid in place of nicotinic acid leading to 2MN and 6MN, respectively

The American Cancer Society recently highlighted the role of our flagship smoke-free product in the rapid decline in cigarette sales in Japan, which has seen its rate of decline in cigarette sales quintuple from a 2 percent decline per year from 2011 through 2015 to a 10 percent decline per year from 2015 through 2018, all without a major change in national tobacco control policy

Logic pods, including those for the Pro and Power ranges, come pre-filled with e-liquid and are not designed for refilling

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Retrieved 2021-02-01