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Moreover, elevated systemic concentrations of TMAO enhanced thrombosis potential in vivo in animal models (4), and in recent clinical intervention studies, elevation in plasma TMAO induced with dietary choline supplementation altered platelet hyperresponsiveness in subjects (omnivores and vegans/vegetarians alike), as monitored by platelet aggregometry (17)

A rodent model where the correlated functional connectivity and metabolism is observed would thus be valuable, as both noninvasive medical imaging and invasive neuroscience experiments could be performed

Research published in the journal Diabetes, Obesity and Metabolism confirms that GLP-1 receptor agonists reduce intestinal transit time through direct action on smooth muscle cells lining the gut wall

demonstrated that memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation

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