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2007;86(2):218-22. PMID: 17364286

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228 There is growing evidence to support the role of GLP-1 receptor agonists and GIP/GLP-1 receptor agonists in improving heart failure-related symptoms and quality of life in people with HFpEF in the setting of obesity, 278,279 and in concurrent obesity and type 2 diabetes

The resulting inflammation creates a painful cycle where swelling leads to more impingement which causes more swelling