Common risk factors for NAION include: Diabetes High blood pressure High cholesterol Sleep apnea Small or crowded optic nerves Smoking Cardiovascular disease Older age These risk factors are important because many patients who take GLP-1 medications may already have diabetes, obesity, sleep apnea, or vascular risk factors that can also increase NAION risk
(ref) Chang CH, Tsai WC, Hsu YH, Pang JH
Modulation of post-antibiotic bacterial community reassembly and host response by Candida albicans
In China, GLP-1 agonists could therefore serve as the catalyst for weight loss before those crucial lifestyle changes kick in
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