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FDA approves weight management drug

Severe complications of SJS/TEN include respiratory failure, shock, functional volume depletion, and infections

The modification involves replacing the glutamic acid at position 3 with arginine (R3) , and extending the N-terminal region by 13 additional amino acids (MFPAMPLLSLFVN), resulting in a longer peptide chain of 83 amino acids compared to the native 70 in human IGF-1

Results are presented visually by treatment cohort and T2DM status at 12 months in this study, but data points and sample sizes are not stated, preventing interpretation and comparison of outcomes with those from the current study [25]

However, it originally emerged as a breakout treatment for type 2 diabetes years ago