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In autoimmune conditions, including RA and SLE, IL-2 production is significantly diminished, which contributes to the characteristic decline in Treg cell frequency and functional impairment, thereby disrupting immune tolerance (263265)

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Intra-articular drug delivery systems for osteoarthritis therapy: shifting from sustained release to enhancing penetration into cartilage

The increased liver levels of acyl-carnitines suggests futile attempts to recycle free CoA from acyl-CoA, and serve as alternative source of energy for brown fat 49 (Extended Data Fig

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