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This distinction is critical
Animal research provides valuable mechanistic understanding but doesn't guarantee identical effects or safety in humans
First, while not much is known about plant mPGES-2s, mammalian mPGES-2s exhibit a dual subcellular localization associated to both the Golgi membrane through their N-terminal part and the cytoplasm after proteolytic cleavage of the N-terminal hydrophobic domain (Tanikawa et al., 2002
Generally, a daily intake of 500 mg to 2,000 mg is recommended for those looking to enhance exercise performance or support weight loss
The N-end rule pathway and regulation by proteolysis
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