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Other Factors That Regulate Ferroptosis Besides the above pathways, there are many other factors that are involved in the regulation of ferroptosis, including Se, NADPH, thioredoxin, transsulfuration pathway, glutaminolysis and nuclear factor erythroid 2-related factor 2 (NRF2) (Figure 3)

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When glutathione is combined with selenium, the two work together more effectively than either one alone