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While many adipose tissue-on-a-chip platforms have been used to study obesity and metabolic disorders (Yang et al., 2021

1- Weight Loss Results: In a Phase II trial [3], retatrutide achieved up to 24.2% average body weight reduction after 48 weeks of treatment in adults with obesity but without diabetes

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MTX, a folic acid analog, inhibits DNA synthesis by blocking thymidine and purine biosynthesis

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