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It has recently been shown that GLP-1R neurons in the dorsomedial hypothalamic nucleus regulate pancreatic activity by affecting the dorsal motor nucleus of the vagus, specifically lowering blood glucose levels by increasing insulin release (Xie et al., 2022)

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Evaluation for sex hormonebinding globulin (SHBG), decreased in in women with PCOS, was also unfeasible due to the absence of postnatal SHBG secretion in mice ( Statements Data availability statement The data presented in the study are deposited in the NCBI Sequence Read Archive database, accession number PRJNA1020997