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In patients with AD, an increase in astrocyte-derived circulating exosomes has been observed, which transport proinflammatory cytokines, supporting the idea that reactive astrocytes contribute to inflammation 56

In vitro CSE exposure Human bronchial epithelial cell line (16HBE, ATCC) was grown in DMEM supplemented with glutamine, 10% FBS and antibiotics

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In murine models of acute liver failure, early-stage liver stem cells (LSCs) demonstrate superior hepatoprotective effects compared to mature hepatocytes