Glutathione dysregulation and the etiology and progression of human diseases.Biol Chem
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In this paper, PTX-induced gastroprotection and accompanying increase in the GBF were attenuated by L-NNA, that nonspecifically inhibits both, cNOS and iNOS forms, indicating that NO, produced by these enzymes in smaller amounts, plays an important role in the protective and hyperemic effects of PTX, a TNFalpha inhibitor
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Therefore, the incidence of DR may have been underestimated