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Consult with your healthcare provider to find the right duration for you

They include 'overactive' immune system disorders, which is when the bodys immune system attacks and destroys its own tissue, and 'underactive' system disorders, which is when the bodys defence against disease is reduced

B12 requires active folate (5-methyltetrahydrofolate) to function properly in the methionine synthase reaction, but folate levels are often low in people with MTHFR variants

Office of Dietary Supplements - Vitamin B12. Nih.gov, 27 Feb

Methionine is also helpful in preventing fatigue and may be useful in some cases of allergies as it can reduce histamine release