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A randomized controlled trial published in the World Journal of Gastroenterology demonstrated that vitamin C supplementation reduced markers of oxidative stress and inflammation in patients with Crohn's disease, highlighting its role in mitigating gut inflammation and improving clinical outcomes (Meyer et al., 2019)

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The organic phases were combined, washed twice with saturated brine, dried over anhydrous sodium sulfate, and purified to obtain a white solid product S1 (240.4 mg, purity 92%)

These mechanisms appear to be down-regulated to maintain the normal methionine levels (Fig