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In particular, we would be interested in knowing if there is a single, common mechanism for all gateway drugs or if each drug utilizes a distinct mechanism. If nicotine works similarly in people, effective smoking cessation efforts might reduce the risk of addiction to cocaine and other illicit drugs.

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The redox equilibrium of DCs has been shown to determine the outcome of T-cell polarization, implicating that ROS and their metabolic intermediates might be involved in allergic sensitization

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