Similar to the findings of other studies in the STEP trial program 7,27 , exploratory outcomes showed that in the semaglutide group 80% of participants with prediabetes at baseline reverted to normoglycemia by the end of the trial (compared with 37% of those receiving placebo), while 99% of participants with normoglycemia at baseline maintained normoglycemia at the end of the trial (compared with 86% with placebo)
It is recommended that those following the semaglutide diet consume mostly whole food sources such as fruits, vegetables, whole grains, and lean proteins like eggs, nuts, and legumes
It will typically remain potent for several weeks when stored properly
GLP-1 inhibits glucagon secretion under hyperglycaemic conditions and thereby improves glycaemia
While mtROS generation serves as a signaling cue for immune activation, excessive accumulation leads to oxidative stress, mtDNA damage, and mitochondrial permeability transition