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Frames with 0.1 ps intervals were extracted (see Supplementary Data 1) and used as starting structures for the US simulation windows

Solubility: Highly soluble in water (130g/L at 25C)

To prevent complications, we brewed 1 L of roasted coffee without added flavors (1 L of water and two tablespoons of coffee), allowed the coffee to cool to room temperature, and then administered it to relatively healthy patients

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and persistent changes in neurotransmitter dynamics initiated during the brief active window