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Dose optimization and positioning strategy will be critical for differentiation
December Dec 26: Accelerated approval doesnt always equal full clearance, something Amgen was reminded of when the FDA declined to convert Lumakras May 2021 conditional nod in KRASG12C-mutated non-small cell lung cancer (NSCLC) to a traditional one
PubMed Central , doi:10.17179/excli2016-485
Applying firm pressure to the injection site for 30-60 seconds after withdrawing the needle can reduce bruising by up to 70%
It has the highest level of clinical evidence (Phase 3 trials, HIV lipodystrophy)
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