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SGLT-2 inhibitors retain adjunctive roles, often combined for cardiorenal protection, while amylin analogues remain niche given specificity to postprandial control

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These side effects are typically mitigated by starting at a low dose, but they can recur when the dose is increased, presenting a risk to patient adherence

Physical Activity Regular Exercise : Aim for at least 150 minutes of moderate-intensity exercise per week