The MOA links the exposure of a cell to a substance that reflects the outcome of interest, for example, increasing cancer risk, and does this in the context of human relevance
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Carbon monoxide is a deadly, odorless, colorless gas that can spread through a home as the result of a malfunctioning or improperly installed chimney or combustion appliance such as a gas stove, a gas boiler, a water heater, a propane range, or a wood stove, according to the Environmental Protection Agency and other sources
"THE ASHTRAY TEST DEMONSTRATES DRAWBACKS OF INTERIOR DESIGN"
But its not all that long ago that cigarettes were warmly welcomed into society and millions suffered and still suffer the cancers to show for it