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GLP-1RAs can influence the composition of the phospholipid layer on cartilage, leading to beneficial effects on joint health and potentially facilitating repair of existing damage in individuals with OA GLP-1RAs in nervous system In the nervous system, GLP-1 can decrease oxidative stress and inflammatory responses, potentially through reducing the generation of ROS and decreasing the expression of inflammatory cytokines
Nicotinamide riboside, a precursor to NAD+, is a form of Vitamin B3
15 Participants: A total of 251 adolescents were enrolled and randomized to receive either liraglutide (3.0 mg once daily) or placebo
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