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Instead, peripherally administered GLP-1 analogs access the brain via circumventricular organsregions bordering the third and fourth ventricles where the barrier is specialized to permit signaling between blood and cerebrospinal fluid

Besides nutrient availability, this process is regulated also by other stimuli, including mechanical stretch, and neural signals

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It also acts as a precursor for erythritol, a known biomarker or signaler for type 2 diabetes, central obesity, and cardiovascular disease

Electrochemical synthesis of chitosan/silver nanoparticles multilayer hydrogel coating with pH-dependent controlled release capability and antibacterial property n.d Azri FA, Selamat J, Sukor R, Yusof NA