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It has been shown that tirzepatide can lower the risk of ASCVD by improving lipid, glucose, and HbA1c levels, as well as blood pressure and waist circumference

One participant in the higher-exposure group developed cardiomyopathy

As a member of TGF- superfamily, BMP4 promotes epithelial-mesenchymal transition (EMT) via the canonical Smad signaling pathway, thereby driving tumor cell metastasis and invasion

Only three GLP-1 drugs are FDA-approved specifically for chronic weight management in people without diabetes: Wegovy (semaglutide), Zepbound (tirzepatide), and Saxenda (liraglutide), plus the oral Wegovy semaglutide pill