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It can also restrict a persons activity and mobility, which in turn can exacerbate problems that tend to diminish health and quality of life in older adults problems such as social isolation, depression, and muscle loss, known as sarcopenia

As a GHRH secretagogue that is subcutaneously injected, ipamorelin likely causes side effects related to frequent injections such as pain, rash or soreness at injection sites, in common with other forms of GH therapies [19]

The lack of established safe dosages and clinical oversight increases the risk of adverse effects

We assume each is Michaelis-Menten and take the K m values from[16]

The complete list of significant comparisons can be found in Additional file 3 and depicted in Fig