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However, its important to keep the following in mind: ALA is not a substitute for statins or other prescription cholesterol medications The lipid-lowering effect is generally modest, especially in healthy individuals or those already on treatment Dose and duration matter most benefits are seen at 6001,200mg/day over 8+ weeks Antioxidant and anti-inflammatory effects: moderate evidence ALA is best known for its antioxidant activity and thats not just in theory

doi: 10.3389/fpsyt.2022.1076459

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They may recommend adjusting doses, spacing supplements and medications apart, or substituting berberine with an alternative metabolic support agent