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The molecule is very large, making it difficult for the skin to absorb effectively from the surface

Figure 26: Photograph of Professor Jens Holst with Dr Karen Thorne, a member of his laboratory, carrying out an experiment with a perfused pig pancreas in the 1990s, credit: Holst

Annals of Pharmacotherapy, 44 (5), 904909.

For example, high levels of vitamin K in foods like leafy green vegetables can counteract the effect of warfarin, leading to a higher risk of clotting

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