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However, resistance training and high-intensity interval training (HIIT) also play crucial roles in the effectiveness of exercise interventions for obesity management (2, 52)
For context, Roux-en-Y gastric bypass surgery weakens this circuit by approximately four-fold, which partly explains why surgical outcomes often exceed pharmaceutical ones in total weight lost
An early clinical report in 1994 described significant clinical improvements in patients treated with DFO (Duarte-Silva et al., 2025)
Agbai ON, Buster K, Sanchez M, Hernandez C, Kundu RV, Chiu M, et al
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