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This metal preferentially accumulates in renal and reproductive tissues, where it compromises the blood-testis barrier integrity and substantially impairs sperm quality parameters (11)

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A chimaeric 11 -hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension

Therefore, the causal inferences drawn in this review should be interpreted with caution, acknowledging that the efficacy observed may be partially influenced by these methodological gaps