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It has been hypothesized that the somnogenic effects of GSSG are due to its ability to attenuate glutamatergic neurotransmission in the brain and stimulate nitric oxide synthase or general oxidative stress signaling mechanisms [19,20]

In comparison, the region that contains the greatest amount of variability between GST classes is contained in the alpha-2 helix on the C-terminal domain

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Reduced Intestinal Inflammation How it works: It lowers pro-inflammatory markers in the gut, helping conditions like Crohns disease and ulcerative colitis

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