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In California, Matthew Barlow, a 48-year-old health technology executive, said he has lost more than 100 pounds since November by using Mounjaro and changing his diet

A multidisciplinary expert consensus published in Frontiers in Endocrinology recommends starting with osmotic laxatives (MiraLAX or magnesium) and only escalating to stimulant laxatives if osmotic options prove insufficient after 2-3 weeks of consistent use

Long-term Digestive Adaptations Over time, the body gets used to not having a gallbladder

Less Common Side Effects Although rare, some individuals may experience: Dizziness Nausea Increased appetite Flu-like symptoms Anyone experiencing persistent or severe symptoms should stop use and seek medical advice