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2014, Haje & Naoom 2015) or no treatment (Dimitriadis et al

doi: 10.1016/j.cmet.2018.10.001

A so-called second-meal effect has been described for fermentable fibers to modulate glycaemic responses and appetite not only at the first subsequent meal after consumption but also at later meals on the same or even subsequent days due to colonic fermentation and increased production of SCFA [10, 11]

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BACKGROUND: Incretin-based therapies such as glucagon-like peptide-1 receptor agonists (GLP-1Ras), dual GLP-1/GIP agonists and amylin analogues have demonstrated significant weight loss benefits