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If GLP-1 medications do benefit psoriasis, the effect is most plausibly mediated through substantial weight loss rather than direct drug action on skin

has acted as a consultant and received honoraria from Boehringer Ingelheim, Eli Lilly, Merck, Novo Nordisk and Sanofi and has received research operating funds from the Boehringer IngelheimEli Lilly Diabetes Alliance, MSD, AstraZeneca and Novo Nordisk

Obesity is one factor that has "stalled progress in life expectancy," as it is linked to 70% of the leading causes of death in high-income countries, according to the researchers

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For example, a study has documented up to a tenfold rise in TMAO levels in healthy individuals after LC supplementation [24]