The efficacy and safety of acetyl-l-carnitine (500 mg three times a day) versus methylcobalamin (0.5 mg three times a day) to treat diabetic peripheral neuropathy was assessed in a Chinese multicentre, randomised, parallel-group, double-blind, double-dummy, positive-controlled, non-inferiority phase II clinical trial
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It must be taken first thing on an empty stomach with a very specific absorption window, so its best to skip the missed dose and wait until the next morning to take your usual dose
Most side effects are gastrointestinal, most appear during dose escalation, and most fade
Most people on Retatrutide tolerate 1,0001,500mg supplemental sodium daily without issues.