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If twice daily, then administer once in the early morning, two hours prior to breakfast, and once in the evening, two hours following the subjects meal

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Niacinamida (Vitamina B3):Mejora el metabolismo celular, fortalece la barrera de la piel desde dentro, reduce hiperpigmentacin y manchas oscuras, aumenta la produccin de colgeno, regula la produccin de sebo

Oral supplementation at higher doses can also treat vitamin B12 deficiency